InteGen LLC was founded in 2011 by an experienced board-certified clinical cytogeneticist to address the challenges often faced by the cytogeneticists in their clinical practice.
In the diagnostic cytogenetics laboratories, it is common to have culture failures (“No Growth”). The extent of the failure depends mostly on the specimen source. In products of conception (POC) material, the failure rates can be as high as 40%. It is not uncommon to have a 50% failure rate for the peripheral blood samples from patients with hematologic malignancies. A small percent of bone marrow samples also fail to produce metaphase chromosomes.
InteGen LLC was started based on a patented technology termed Interphase Chromosome Profiling (ICP). The concept is very simple. Individual chromosomes are studied in their uncondensed state in an interphase nucleus using a panel of FISH probes that target DNA sequences in an equidistant fashion along the entire length of the chromosome. ICP overcomes the major drawbacks associated with the classical approach of studying individual chromosomes by targeting the chromosome in an interphase nucleus rather than the standard metaphase.
InteGen LLC is committed to providing clinically useful and cost-effective tools for the cytogenetics community.
The Chief attributes of ICP are:
- Novel patented technology
- Developed by a clinical cytogeneticist
- Fast and Failure-proof
- Sensitive and Cost-effective
- Marker chromosome identification
- Characterization of “add” material
- One-stop “global FISH” approach
NO MORE NO GROWTH with ICP
Never Again Sign a Failed Cytogenetics Report